Three changes for Roma from the team that started the first leg on 24 April.
Italy midfielder Lorenzo Pellegrini, Patrik Schick, who is on loan from Sampdoria, and Greece defender Kostas Manolas are in the side.
Juan Jesus, Kevin Strootman, who has a knock, and Cengiz Under drop out.
Roma XI: Alisson, Florenzi, Fazio, Manolas, Kolarov, Nainggolan, Rossi, Pellegrini, Schick, Dzeko, El Shaarawy.
Just the one change for Liverpool from the first leg as midfielder Georginio Wijnaldum replaces Alex-Oxlade Chamberlain, who is out with a serious knee injury.
Liverpool XI: Karius, Robertson, Van Dijk, Lovren, Arnold, Milner, Henderson, Wijnaldum, Mane, Firmino, Salah.