Liverpool are understandably favourites to reach the semi-finals of the Champions League for the first time since 2008 but there is one cause for concern.
The Reds have never won an away match against English opposition in European competition.
Their first away game to an English side was back in 1971 – when they faced Leeds in the 1970-71 Inter-Cities Fairs Cup and drew 0-0 – and in the nine games since then they have failed to pick up any wins on the road.
Man City: Ederson, Walker, Otamendi, Laporte, Bernardo Silva, Fernandinho, De Bruyne, Silva, Sterling, Gabriel Jesus, Sane. Subs: Bravo, Kompany, Gundogan, Aguero, Delph, Zinchenko, Foden.
Liverpool: Karius, Alexander-Arnold, Lovren, van Dijk, Robertson, Oxlade-Chamberlain, Wijnaldum, Milner, Salah, Firmino, Mane. Subs: Mignolet, Clyne, Klavan, Moreno, Ings, Solanke, Woodburn.