Bayern Munich manager Jupp Heynckes has left experienced duo Franck Ribery and Arjen Robben on the bench tonight.
They are replaced by skipper Thomas Muller and left-back David Alaba, who were both among the substitutes for Saturday’s 2-1 win at Wolfsburg.
Bayern are bidding to reach the quarter-finals for a seventh year in a row and this is their 14th time in the last 16.
Besiktas became the first Turkish team to win their Champions League group when they saw off RB Leipzig, Porto and Monaco in Group G.
This is the only last 16 tie featuring two reigning domestic champions.
Bayern Munich: Ulreich, Hummels, Boateng, Alaba, Kimmich, Martínez, Vidal, Rodríguez Müller(c), Lewandowski, Coman.
Subs: Wagner, Süle, Starke, Robben, Tolisso, Rafinh, Ribéry.
Beskitas: Fabri, Adriano, Erkin, Vida, Pepe, Hutchinson(c), Medel, Quaresma, Talisca, Babel, Love
Subs: Tosic, Lens, Zengin, Negredo, Gönül, Arslan, Ozyakup.